What are TNF inhibitors?
TNF inhibitors are a class of biologic therapies that include adalimumab (Humira®), infliximab (Remicade®), and several other medications. TNF inhibitors are used to treat several forms of vasculitis, including Takayasu’s, Behcet’s, and some types of cutaneous vasculitis.
How do TNF inhibitors work?
These drugs block the function of TNF alpha – a protein involved in driving inflammation.
How are TNF inhibitors given?
Some TNF inhibitors can be given as self-injection (adalimumab). Others are administered intravenously in an infusion center (infliximab). The dosing intervals of these drugs are generally in the range of 1 to 4 weeks.
We pay particular attention to a history of TB prior to starting TNF inhibitors.
All immunosuppressants require regular monitoring in the form of blood tests, in-person assessments, and vigilance for signs of infection.